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* Equally contributed first author, † Corresponding author

  1. Nagase N, Kousaki H, Ogawa B, Horii K, Morimoto IN, Abe C, Ogawa T, Nin F. Two-tone suppression between the ultrasounds above and within the hearing range in mice. Exp Physiol. 2025 Feb 23.

  2. Okamura Y, Gochi K, Ishikawa T, Hayashi T, Fuseya S, Suzuki R, Kanai M, Inoue Y, Murakami Y, Sadaki S, Jeon H, Hayama M, Ishii H, Tsunakawa Y, Ochi H, Sato S, Hamada M, Abe C, Morita H, Okada R, Shiba D, Muratani M, Shinohara M, Akiyama T, Kudo T, Takahashi S. Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel. Sci Rep. 2024 Nov 20;14(1):28774.

  3. Bazek M, Sawa M, Horii K, Nakamura N, Iwami S, Wu CH, Inoue T, Nin F, Abe C†. Gravitational change-induced alteration of the vestibular function and gene expression in the vestibular ganglion of mice. J Physiol Sci. 2024 Sep 18;74(1):44.

  4. Horii K, Ogawa B, Nagase N, Morimoto I, Abe C, Ogawa T, Choi S, Nin F. The cochlear hook region detects harmonics beyond the canonical hearing range. PNAS Nexus. 2024 Jul 12;3(7):pgae280.

  5. Heishima K, Sugito N, Abe C, Hirata A, Sakai H, Akao Y. Targeting microRNA-145-mediated progressive phenotypes of early bladder cancer in a molecularly defined in vivo model. Molecular Therapy Nucleic Acids. 2023 Jul 3:33:960-982.

  6. Abe C†, Katayama C, Bazek M, Ohbayashi K, Horii K, Tanida M, Nin F, Iwasaki Y. Hepatic glycogenolysis and hypometabolism induced by chemogenetic stimulation of C1 neurons. J Physiol. 2023 Jun;601(12):2293-2306.

  7. Hayashi T, Fujita R, Okada R, Hamada M, Suzuki R, Fuseya S, Leckey J, Kanai M, Inoue Y, Sadaki S, Nakamura A, Okamura Y, Abe C, Morita H, Aiba T, Senkoji T, Shimomura M, Okada M, Kamimura D, Yumoto A, Muratani M, Kudo T, Shiba D, Takahashi S. Lunar gravity prevents skeletal muscle atrophy but not myofiber type shift in mice. Commun Biol. 2023 Apr 21;6(1):424. 

  8. Abe C†, Katayama C, Bazek M, Nakamura Y, Ohbayashi K, Horii K, Fujimoto C, Tanida M, Iwasaki Y, Inoue T, Nin F, Morita H. Repeated activation of C1 neurons in medulla oblongata decreases anti-inflammatory effect via the hypofunction of the adrenal gland adrenergic response. Brain Behav Immun. 2023 Apr 8;111:138-150.

  9. Abe C†, Katayama C, Ohbayashi K, Horii K, Ogawa B, Fujimoto C, Iwasaki Y, Nin F, Morita H. Galvanic vestibular stimulation-induced activation of C1 neurons in medulla oblongata protects against acute lung injury. Am J Physiol Regul Integr Comp Physiol. 2023 Feb 1;324(2):R152-R160.

  10. Abe C†, Katayama C, Horii K, Okada R, Kamimura D, Nin F, Morita H. Changes in metabolism and vestibular function depend on gravitational load in mice. J Appl Physiol. 2023 Jan 1;134(1):10-17. 

  11. Abe C†, Katayama C, Horii K, Ogawa B, Ohbayashi K, Iwasaki Y, Nin F, Morita H. Hypergravity load-induced hyperglycemia occurs due to hypothermia and increased plasma corticosterone level in mice. J Physiol Sci. 2022 Aug 1;72(1):18.

  12. Tanaka S, Abe C, Abbott SBG, Zheng S, Yamaoka Y, Lipsey JE, Skrypnyk NI, Yao J, Inoue T, Nash WT, Stornetta DS, Rosin DL, Stornetta RL, Guyenet PG, and Okusa MD. Vagus nerve stimulation activates two distinct neuroimmune circuits converging in the spleen to protect mice from kidney injury. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2021758118.

  13. Aoki H, Abe C, Hara A, Miyazaki T, Morita H, Kunisada T. Induced genetic ablation of Rest leads to the alteration of stimulus-induced response of the vagal nerve. Genes Cells. 2021 Feb;26(2):45-55.

  14. Abe C*†, Yamaoka Y*, Maejima Y, Mikami T, Yokota S, Yamanaka A, Morita H†. VGLUT2-expressing Neurons in the Vestibular Nuclear Complex Mediate Gravitational Stress-Induced Hypothermia in Mice. Commun Biol. 2020 May 8;3(1):227.​

  15. Abe C†, Yamaoka Y, Maejima Y, Mikami T, Morita H. Hypergravity-induced plastic alteration of the vestibulo-sympathetic reflex involves decrease in responsiveness of CAMK2-expressing neurons in the vestibular nuclear complex. J Physiol Sci. 2019 Nov;69(6):903-917.

  16. Sugiyama K, Nagashima K, Miwa T, Shimizu Y, Kawaguchi T, Iida K, Tamaoki N, Hatakeyama D, Aoki H, Abe C, Morita H, Kunisada T, Shibata T, Fukumitsu H, Tezuka KI. FGF2-responsive genes in human dental pulp cells assessed using a rat spinal cord injury model. J Bone Miner Metab. 2019 May;37(3):467-474

  17. Inoue T, Abe C, Kohro T, Tanaka S, Huang L, Yao J, Zheng S, Ye H, Inagi R, Stornetta RL, Rosin DL, Nangaku M, Wada Y, Okusa MD. Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/ reperfusion injury in the kidney. Kidney Int. 2019 Mar;95(3):563-576.

  18. Sonoda S, Yoshimura M, Abe C, Morita H, Ueno H, Motojima Y, Saito R, Maruyama T, Hashimoto H, Tanaka Y, Ueta Y. Effects of hypergravity on the gene expression of the hypothalamic feeding-related neuropeptides in mice via vestibular inputs. Peptides. 2018 Jul;105:14-20.

  19. Yamaoka Y, Abe C†, Morita H. Comparison among ultrasonic, electrical apparatus, and toxic chemicals for vestibular lesion in mice. J Neurosci Methods. 2017 Dec 2;295:58-67.

  20. Abe C*, Inoue T*, Inglis MA, Viar KE, Huang L, Ye H, Rosin DL, Stornetta RL, Okusa MD, Guyenet PG. C1 neurons mediate a stress-induced anti-inflammatory reflex in mice. Nat Neurosci. 2017 May;20(5):700-707.

  21. Wenker IC, Abe C, Viar KE, Stornetta SL, Stornetta RL, Guyenet PG. Blood pressure regulation by the rostral ventrolateral medulla in conscious rats: effects of hypoxia, hypercapnia, baroreceptor denervation and anesthesia. J Neurosci. 2017 Apr 26;37(17):4565-4583.

  22. Morita H, Abe C, Tanaka K. Long-term exposure to microgravity impairs vestibulo-cardiovascular reflex. Sci Rep. 2016 Sep 16;6:33405.

  23. Shi Y, Abe C, Holloway BB, Shu S, Kumar NN, Weaver JL, Sen J, Perez-Reyes E, Stornetta RL, Guyenet PG, Bayliss DA. Nalcn is a "leak" sodium channel that regulates excitability of brainstem chemosensory neurons and breathing. J Neurosci. 2016 Aug 3;36(31):8174-87.

  24. Basting TM, Abe C, Viar KE, Stornetta RL, Guyenet PG. Is plasticity within the retrotrapezoid nucleus responsible for the recovery of the PCO2 set-point after carotid body denervation in rats? J Physiol. 2016 Jun 15;594(12):3371-90.

  25. Inoue T*, Abe C*, Sung SJ, Moscalu S, Jankowski J, Huang L, Ye H, Rosin DL, Guyenet PG, Okusa MD. Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes. J Clin Invest. 2016 May 2;126(5):1939-52.

  26. Morita H, Obata K, Abe C, Shiba D, Shirakawa M, Kudo T, Takahashi S. Feasibility of a Short-Arm Centrifuge for Mouse Hypergravity Experiments. PLoS One. 2015 Jul 29;10(7):e0133981.

  27. Abe C, Nagai Y, Yamaguchi A, Aoki H, Shimizu S, Akiyama T, Kawada T, Sugimachi M, Morita H. Reduced carotid baroreceptor distensibility-induced baroreflex resetting contributes to impairment of sodium regulation in rats fed a high-fat diet. Am J Physiol Heart Circ Physiol. 2015 Apr 15;308(8):H942-50.

  28. Iwata C, Abe C, Nakamura M, Morita H. Hypergravity exposure for 14 days increases the effects of propofol in rats. Anesth Analg. 2014 Jan;118(1):125-31.

  29. Abe C, Morita H. Drinking-induced bradyarrhythmias and cerebral injury in Dahl salt sensitive rats with sinoaortic denervation. J Appl Physiol. 2013 Nov;115(10):1533-9.

  30. Abe C, Ueta Y, Morita H. Exposure to hypergravity during the preweaning but not postweaning period reduces vestibular-related stress responses in rats. J Appl Physiol. 2013 Oct 1;115(7):1082-7.

  31. Tanaka K, Nishimura N, Sato M, Kanikowska D, Shimizu Y, Inukai Y, Abe C, Iwata C, Morita H, Iwase S, Sugenoya J. Arterial pressure oscillation and muscle sympathetic nerve activity after 20 days of head-down bed rest. Auton Neurosci. 2013 Oct;177(2):266-70.

  32. Abe C, Iwata C, Morita H. Water drinking-related muscle contraction induces the pressor response via mechanoreceptors in conscious rats. J Appl Physiol. 2013 Jan;114(1):28-36.

  33. Abe C, Tsuru Y, Iwata C, Ogihara R, Morita H. Intravenous infusion of hyperosmotic NaCl solution induces acute cor pulmonale in anesthetized rats. J Physiol Sci. 2013 Jan;63(1):55-62.

  34. Cuong NT, Abe C, Binh NH, Hara A, Morita H, Ogura S. Sivelestat improves outcome of crush injury by inhibiting high-mobility group box 1 in rats. Shock. 2013 Jan;39(1):89-95.

  35. Tanaka K, Abe C, Sakaida Y, Aoki M, Iwata C, Morita H. Subsensory galvanic vestibular stimulation augments arterial pressure control upon head-up tilt in human subjects. Auton Neurosci. 2012 Jan 26;166(1-2):66-71.

  36. Abe C, Kawada T, Sugimachi M, Morita H. Interaction between vestibulo-cardiovascular reflex and arterial baroreflex during postural change in rats. J Appl Physiol. 2011 Dec;111(6):1614-21.

  37. Abe C, Iwata C, Shiina T, Shimizu Y, Morita H. Effect of daily linear acceleration training on the hypergravity-induced vomiting response in house musk shrew (Suncus murinus). Neurosci Lett. 2011. Sep 20;502(3):138-42.

  38. Matsuo O, Takahashi Y, Abe C, Tanaka K, Nakashima A, Morita H. Trial of integrated laboratory practice. Adv Physiol Educ. 2011 Jun;35(2):237-40.

  39. Iwata C, Abe C, Tanaka K, Morita H. Role of the vestibular system in the arterial pressure response to parabolic-flight-induced gravitational changes in human subjects. Neurosci Lett. 2011 May 16;495(2):121-5.

  40. Abe C, Tanaka K, Iwata C, Morita H. Vestibular-mediated increase in central serotonin plays an important role in hypergravity-induced hypophagia in rats. J Appl Physiol. 2010 Dec;109(6):1635-43.

  41. Abe C, Shibata A, Iwata C, Morita H. Restriction of rear-up-behavior-induced attenuation of vestibulo-cardiovascular reflex in rats. Neurosci Lett. 2010 Oct 22;484(1):1-5.

  42. Tanaka K, Tohnan M, Abe C, Iwata C, Yamagata K, Tanaka M, Tanaka N, Morita H. Development and evaluation of gas-pressurized elastic sleeves for extravehicular activity. Aviat Space Environ Med. 2010 Jul;81(7):671-6.

  43. Tanaka K, Abe C, Iwata C, Yamagata K, Murakami N, Tanaka M, Tanaka N, Morita H. Mobility of a gas-pressurized elastic glove for extravehicular activity. Acta Astronautica. 2010 Apr-May;66(7-8):1039-1043.

  44. Abe C, Tanaka K, Awazu C, Morita H. Galvanic vestibular stimulation counteracts hypergravity-induced plastic alteration of vestibulo-cardiovascular reflex in rats. J Appl Physiol. 2009 Oct;107(4):1089-94.

  45. Tanaka K, Abe C, Awazu C, Morita H. Vestibular system plays a significant role in arterial pressure control during head-up tilt in young subjects. Auton Neurosci. 2009 Jun 15;148(1-2):90-6.

  46. Abe C, Tashiro T, Tanaka K, Ogihara R, Morita H. A novel type of implantable and programmable infusion pump for small laboratory animals. J Pharmacol Toxicol Methods. 2009 Jan-Feb;59(1):7-12.  

  47. Abe C, Tanaka K, Morita H. The vestibular system is integral in regulating plastic alterations in the pressor response to free drop mediated by the nonvestibular system. Neurosci Lett. 2008 Nov 14;445(2):149-52.

  48. Abe C, Tanaka K, Awazu C, Morita H. Impairment of vestibular-mediated cardiovascular response and motor coordination in rats born and reared under hypergravity. Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R173-80.

  49. Abe C, Tanaka K, Awazu C, Morita H. Strong galvanic vestibular stimulation obscures arterial pressure response to gravitational change in conscious rats. J Appl Physiol. 2008 Jan;104(1):34-40.

  50. Morita H, Abe C, Awazu C, Tanaka K. Long-term hypergravity induces plastic alterations in vestibulo-cardiovascular reflex in conscious rats. Neurosci Lett. 2007 Feb 2;412(3):201-5.

  51. Abe C, Tanaka K, Awazu C, Chen H, Morita H. Plastic alteration of vestibulo-cardiovascular reflex induced by 2 weeks of 3-G load in conscious rats. Exp Brain Res. 2007 Aug;181(4):639-46.

  52. Morita H, Abe C, Tanaka K, Shiratori M, Oguri M, Shiga T. Neuromuscular electrical stimulation and ottoman-type seat effectively improve popliteal venous flow in sitting position. J Physiol Sci. 2006 Apr;56(2):183-6.

 

Review

  1. Morita H, Kaji H, Ueta Y, Abe C. Understanding vestibular-related physiological functions could provide clues on adapting to a new gravitational environment. J Physiol Sci. 2020 Mar 14;70(1):17

  2. Abe C†, Inoue T. Role of C1 neurons in anti-inflammatory reflex: Mediation between afferents and efferents. Neurosci Res. 2018 Nov;136:6-12.

  3. Morita H, Abe C. Negative feedforward control of body fluid homeostasis by hepatorenal reflex. Hypertens Res. 2011 Aug;34(8):895-905

​

Book

  1. Uni R, Abe C, Inagi R, and Inoue T. Role of the Nervous System in Acute Kidney Injury. Acute Kidney Injury and Regenerative Medicine. 2020 Chapter 21:297-316

​

国内総説

  1. 安部力：神経系と内分泌系が制御する抗炎症機能，実験医学，41巻20号，3372-3377，2023
  2. 安部力：前庭－血圧反射に注目した重力環境への適応戦略，Precision Medicine，4巻9号，863-868, 2021年

  3. 安部力，森田啓之：前庭系を介する動脈血圧調節，自律神経，58巻1号，95-100，2021年

  4. 安部力，井上剛，Patrice G. Guyenet：急性ストレスによる腎虚血再灌流障害の軽減効果には延髄C1ニューロンが関与する，実験医学，35巻13号，2262-2265，2017

  5. 安部力，森田啓之：動脈血圧調節に対する前庭系の関与：前庭系の可塑性と起立性低血圧，循環制御，36巻2号，69-75，2015

  6. 森田啓之，安部力：宇宙から帰還後の起立性低血圧－前庭系の関与，医学のあゆみ，243巻5号，425-431，2012

  7. 森田啓之，安部力，田中邦彦：起立時の血圧調節における前庭－交感神経反射と圧受容器反射の役割，自律神経，49巻3号，169-172，2012年

  8. 安部力，岩田ちひろ，森田啓之：前庭電気刺激による前庭入力遮断と前庭系の可塑的変化防止，自律神経，49巻3号，173-175，2012年

  9. 安部力，田中邦彦，森田啓之：下肢静脈血行動態の特性から見た深部静脈血栓症，血栓止血誌，19: 495-500, 2008年

 

国内著書

  1. 佐久間康夫，鯉淵典之，安部力ら：生理学用語ハンドブック，2024

  2. 安部力：神経・内分泌系による免疫/炎症制御，集中治療医学，178-180，2023

  3. 松尾　理，安部力，森田啓之，他4名：基礎統合実習－次世代のPhysician Scientistsが育つ場－，39-40, 2012

  4. 岡田隆夫, 安部力，森田啓之，他9名：心臓・循環の生理学, メディカル・サイエンス・インターナショナル，317-353, 2011

  5. 松尾 理, 安部力，森田啓之，他11名：カラー図解　症状の基礎からわかる病態生理　第二版, メディカル・サイエンス・インターナショナル，190-259, 2011

 

Awards

  1. 学会賞, 第72回日本自律神経学会, 2019
    Society Award, Japan Society of Neurovegetative Research

  2. 優秀論文賞, 第60回日本宇宙航空環境医学会, 2014
    The Best Article Award, Japan Society of Aerospace and Environmental Medicine

  3. 平成23年度 入澤宏・彩記念若手研究奨励賞 [心臓・循環分野], 第89回日本生理学会, 2012
    Hiroshi and Aya Irisawa Memorial Promotion Award for Young Physiologists, Physiological Society of Japan

  4. 奨励賞, 第12回Neurocardiology workshop, 2011
    Encouragement award, The 12th Neurocardiology workshop

  5. 優秀賞, 第11回Neurocardiology workshop, 2010
    Award of excellence, The 11th Neurocardiology workshop

  6. Poster presentation award, 30th International Society for Gravitational Physiology, 2009
    Poster Presentation Award, 30th Annual International Gravitational Physiology Meeting

  7. 奨励賞, 第18回日本病態生理学会, 2008
    Young Scientist Presentation Award, Japanese Society of Pathophysiology

 

研究費助成

  1. 2024年度　公益財団法人木下記念事業団　学術研究活動助成事業
    月や火星の重力環境適応を目指した前庭系可塑メカニズムの解明

  2. 2023年度　公益財団法人上原記念生命科学財団　研究助成金
    GLP-1による自律神経活性化を介した抗炎症手法の開発

  3. 2023-2025年度　基盤研究(B)
    食事性神経ー免疫系の活性化で目指す誤嚥性肺炎の予防・軽減と健康寿命延伸戦略

  4. 2023年度　公益財団法人ニッポンハム食の未来財団　共同研究助成
    食物アレルギーに関わる神経－免疫系の機序解明と軽減手法確立への挑戦

  5. 2022-2024年度　挑戦的研究（萌芽）
    口腔内微生物叢の改善を目指す光遺伝学を駆使した唾液分泌制御手法開発への挑戦

  6. 2022年度　公益財団法人三島海雲記念財団　学術研究奨励金​（共同）
    食事による自律神経制御で目指す免疫力の活性化

  7. 2022年度　公益財団法人ソルト・サイエンス研究財団 プロジェクト研究助成金
    塩分摂取が神経－免疫系を介する誤嚥性肺炎の軽減効果に与える影響の解明

  8. 2022年度　公益財団法人喫煙科学研究財団 助成金
    慢性的なニコチン性アセチルコリン受容体刺激が神経－免疫系に与える影響の解明

  9. 2021年度　公益財団法人高橋産業経済研究財団 助成金
    平衡機能低下を防ぐ末梢前庭電気刺激装置の開発

  10. 2020年度　公益財団法人鈴木謙三記念医科学応用研究財団 研究助成
    ​延髄C1ニューロンを介する過食性障害のメカニズム解明

  11. 2019年度　公益財団法人金原一郎記念井医学医療振興財団 基礎医学医療研究助成金
    ​前庭系を介する酸素消費量の調節

  12. 2019年度　公益財団法人武田科学振興財団 医学系研究継続助成
    延髄C1ニューロンの出力異常と過敏性腸症候群の関係解明

  13. 2019-2021年度　基盤研究(C)
    前庭系可塑のメカニズム解明とデコンディショニング治療への展開

  14. ​2019年度　公益財団法人稲盛財団 稲盛研究助成
    前庭－交感神経反射を介する新たな抗炎症機構の解明

  15. 2018年度　公益財団法人第一三共生命科学研究振興財団 研究助成
    延髄C1ニューロンを介する新たな免疫制御機構の解明

  16. 2018年度　公益財団法人持田記念医学薬学振興財団 持田記念研究助成
    延髄C1ニューロンを介する新たな免疫制御機構の解明

  17. 2018-2020年度　新学術領域研究（公募研究）
    重力変化による自律神経系の可塑：前庭系－延髄C1神経細胞連関へのアプローチ

  18. 2017年度　公益財団法人中冨健康科学振興財団 研究助成
    前庭系可塑による協調運動機能低下のメカニズム解明

  19. 2017年度　公益財団法人上原記念生命科学財団 研究奨励金
    前庭系可塑による自律神経応答低下のメカニズム解明

  20. 2017年度　公益財団法人加藤記念バイオサイエンス振興財団 研究助成
    前庭系可塑が引き起こす自律神経応答低下のメカニズム解明

  21. 2016年度　公益財団法人武田科学振興財団 医学系研究奨励
    延髄C1ニューロンの出力異常と過敏性腸症候群の関係解明

  22. 2014 - 2016　日本学術振興会海外特別研究員　
    オプトジェネティクスを用いた中枢での圧受容器反射と化学受容器反射の相互作用解明

  23. 2011 - 2013年度 若手研究(B)
    起立性低血圧における前庭－動脈血圧反射の定量的評価と飲水による改善方法

  24. 2012年度 公益財団法人ソルト・サイエンス研究財団研究助成
    高張NaCl溶液静脈内投与による一過性の動脈血圧低下のメカニズム解明

  25. 2008 – 2009年度 日本学術振興会特別研究員奨励費
    重力環境変化に対する生体適応:将来月面基地で生活するために

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